Manchester United goalkeeper Ben Foster will make his long-awaited debut for the club - three seasons after moving to Old Trafford.
Foster, 24, spent two seasons on loan to Watford before having a knee operation in the summer.
With only one reserve game behind him, he has been drafted in to face Derby at Pride Park as Edwin van der Sar has a groin problem and Tomasz Kuszczak is suspended.
Manager Sir Alex Ferguson has firm belief in Foster, who has one England cap to his name, to do a job after planning to send him out on loan before two of his goalkeepers were sidelined.
He said: "Ben has been out for a year and this is a big challenge for the boy.
"Certain things, though, about him encourage me. He has fantastic presence and speed and agility. I have no fears about him being okay."
Louis Saha (knee) and Ryan Giggs (calf) remain doubtful through injury for the game against the Premier League's bottom club.
Derby defender Alan Stubbs is certain to miss out.
Stubbs suffered a calf injury in Wednesday's 6-1 defeat at Chelsea and is expected to be sidelined for two to three weeks.
Rams boss Paul Jewell will hand a late fitness test to Stephen Pearson, who is struggling with a stomach muscle strain, while Tyrone Mears and Claude Davis remain long-term absentees.
Squads:
Derby: Carroll, Leacock, Moore, Todd, McEveley, Lewis, Edworthy, Savage, Pearson, Jones, Miller, Earnshaw, Ghaly, Villa, Robert, Price, Sterjovski.
Man Utd: Foster, Brown, Vidic, Ferdinand, Evra, Ronaldo, Carrick, Fletcher, Hargreaves, Nani, Rooney, Tevez, Scholes, Giggs, O'Shea, Saha, Anderson, Park, Pique, Heaton.