Juande Ramos has called for a Tottenham performance at the Philips Stadium to match his last match in Eindhoven when he won his first trophy as a manager.
Ramos guided Sevilla to victory over Middlesbrough at the ground in the 2006 UEFA Cup final before defending the competition last season - but his hopes of a hat-trick are in the balance after PSV earned a 1-0 advantage last week.
Spurs need at least a goal to have a chance of reaching the quarter-finals, and Ramos has told his players to attack.
"I have magnificent memories about the first cup we won at Sevilla, it was also my first title," he said.
"It was a beautiful and unforgettable experience, but now we have to think about playing well if we want to stay in this year's competition.
"We are going to need a similar type of performance as Sevilla produced last time here. The players are going to have to play at an extremely high level to get through.
"Tottenham always play to win, whether we start 0-0, winning 1-0 or losing 1-0. We have no other type of football or concept of playing. We are going to play like we always do and nothing more."